Abstract
Computer-assisted superimposition of the equivalent dipole sources (EDSs) of the main pathological EEG patterns with the results of computer tomography and magnetic resonance imaging of the brain was performed for patients with organic CNS lesions. The greatest degree of structural determination was revealed for local and lateralized (in a traumatic injury) slow waves, whose EDSs mapped to the perifocal zone of the injury focus. The EDSs of epileptiform patterns could be located in the zone of damaged brain substance or in the intact hemisphere (when the limbic structures were damaged), reflecting the formation of secondary functional foci in the latter case. Bilateral paroxysmal patterns were more frequently determined by the functional state of the medial brain structures. The EDSs of pathological (diencephalic, hippocampal) α activity were closely associated with the corresponding anatomical brain structures, although without a strict dependence on the degree of their morphological intactness.
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