Abstract
Zinc chloride is an important pharmaceutical/nutraceutical mineral for the prevention and treatment of several diseases. The objective of the current study was to investigate the impact of The Trivedi Effect<sup>®</sup>-Energy of Consciousness Healing Treatment (Biofield Energy Treatment) on physical, structural, thermal, and behavioral properties of zinc chloride using PXRD, PSD, FT-IR, UV-vis, and DSC analysis. Zinc chloride was divided into two parts – one part was control, while another part was treated with The Trivedi Effect<sup>®</sup> remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect<sup>®</sup> treated sample. A significant alteration of the crystallite size and relative intensities of the PXRD peaks were observed in The Trivedi Effect<sup>®</sup> treated sample with respect to the control sample. A sharp peak at 2θ equal to 51.45°, which was observed in the control sample was disappeared in the treated sample. The average crystallite size of the treated sample was decreased by 2.13% compared with the control sample. The size of the particles at d<sub>10</sub>, d<sub>50</sub>, and d<sub>90</sub> was decreased by 3.36%, 7.97%, and 11.51%, respectively in the treated sample compared with the control sample. The surface area of the treated sample was significantly increased by 5.69% compared with the control sample. The FT-IR spectroscopic analysis revealed that Zn-Cl stretching in the control was 646 cm<sup>-1</sup>, whereas it was significantly shifted downward to 505 cm<sup>-1</sup> in the treated sample. The UV-vis analysis exhibited that wavelength of the maximum absorbance (λ<sub>max</sub>) of both the control and treated samples was at 196.4 nm. The DSC analysis exhibited that the melting and decomposition temperature were increased by 0.93% and 0.56%, respectively in the treated zinc chloride compared to the control sample. The enthalpy of fusion of the treated sample (338.27 J/g) was increased significantly by 33.84% compared with the control sample (252.75 J/g). The enthalpy of decomposition of the treated sample was increased by 3.78% compared with the control sample. The current study anticipated that The Trivedi Effect<sup>®</sup>-Energy of Consciousness Healing Treatment might lead to produce a new polymorphic form of zinc chloride, which would be more soluble, bioavailable, and thermally stable compared with the untreated compound. The treated sample could be more stable during manufacturing, delivery or storage conditions than the untreated sample. Hence, the treated zinc chloride would be very useful to design better nutraceutical/pharmaceutical formulations that might offer better therapeutic response against inflammatory diseases, immunological disorders, aging, stress, cancer, etc.
Highlights
Zinc is an essential element in human and animal nutrition for its broad spectrum of biological activities
(2θ), relative intensity (%), full width half maximum 70.7° (Table 1, entry 7, 11, and 13-16) was significantly (FWHM) (θ°), and crystallite size (G) for the control and decreased in the range of 20% to 50% with respect to the Biofield Energy Treated zinc chloride are presented in the control sample
The current study revealed that the Biofield Energy Healing Treatment (The Trivedi Effect®) had the notable effects on the physicochemical and thermal properties of zinc chloride
Summary
Zinc is an essential element in human and animal nutrition for its broad spectrum of biological activities. Zinc chloride (ZnCl2) is hygroscopic inorganic salt and highly soluble in water [9] It is sometimes used in pharmaceutical industry as drug and diagnostic agent due to its powerful astringent and mild antiseptic properties [10]. Literature reported that zinc chloride has been used in the treatment of cancer as a destructive agent [12] and in the pluripotency maintenance of mouse embryonic stem cell through the regulation of STAT3 signaling pathway [13]. It can be used for the palliative treatment of canine and malignant skin wounds [14]. This herbomineral formulation is designed as nutraceutical supplement, and can be used for the prevention and treatment of various human disorders
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