Abstract
Objective: This study was conducted to find out the effect of obesity on immune cells activity and some biochemical markers in women.
 Methods: The experimentation is carried out on 30 voluntary individuals were divided into two groups; 15 women with obesity (Body Mass Index [BMI]>30) were selected, On the other hand, we took 15 witnesses (BMI<30). All the volunteers were subjected to estimate the lipid profile, biochemical, and hematological parameters.
 Results: Results obtained show that there was a significant increase of blood glucose (p<0.05), triglyceride (p<0.05) and uric acid (p<0.001) and no significant change of other biochemical markers in obese people’s group when compared to the control subjects. In addition, the hematological results demonstrated that there was a significant decrease (p<0.05) of lymphocytes, hemoglobin, hematocrit, and mean corpuscular volume levels (p<0.01) in women with obesity compared to the controls.
 Conclusion: Our study reveals that the obesity may be induce the sever alteration in lipid profile which cause the cardiovascular risk for this population. In addition, the obesity causes a remarkable change in some biochemical markers and blood constituent’s anemia or other metabolic disorder in the body.
Highlights
The number of women in our study reached 15 sick women suffering from obesity and 15 other women who were not obese
The results showed an increase in the level of uric acid in obese women, which may explain the effect of this criterion on insulin resistance (IR) to reduce the urine excretion of uric acid
White blood cell count was elevated in obesity [21], studies have found that, there is some sort of association between the increased number of immune cells and obesity as a result of a chronic inflammatory condition which is created by an increase in the production of cytokines by adipose tissue [22]
Summary
The experimentation is carried out on 30 voluntary individuals were divided into two groups; 15 women with obesity (Body Mass Index [BMI]>30) were selected, On the other hand, we took 15 witnesses (BMI30) their mean age is 44.07±12.52 years old. There are 15 other women who are not obese All the volunteers (control and patients) in this study live in the El Oued area located in the southeast of Algeria. Women who have a BMI >30 were organized for the study
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