Abstract
Burns are an actual problem of modern medicine. Oxidative stress, microcirculation, and hemostasis disorders are important links in the pathogenesis of burn disease. It is shown that these processes are significantly influenced by the point effect of low-intensity (LI) electromagnetic radiation (EMR) of the millimeter (MM) and submillimeter (subMM) ranges. However, the final opinion on the advantages of a particular range has not been formed. We have given a comparative assessment of the results of the effects of various frequency-energy parameters of microwaves on the indicators of adaptive reactions in rats under experimental thermal trauma and viscoelastic properties of blood in the case of burn disease.
Highlights
Burns are an actual problem of modern medicine
We used a model of a grade IIIA contact thermal burn, which was applied under intramuscular anesthesia from a combination of “Zoletil-100” (“Virbacsanteanimale,” France), at a dose of 10 mL/kg, and “Xylavet” (“Interchemie,” the Netherlands), at a dose of 10 mg/kg, on the depilated surface of the animal’s back on an area of 20% of the body surface by a single three-second contact of an isolated skin area with a thermal heating element [25]
The study of biochemical parameters of oxidative and energy metabolism in animals of the second control group against the background of contact thermal burn in the absence of radiation revealed the development of oxidative stress
Summary
Burns are an actual problem of modern medicine. Oxidative stress, microcirculation, and hemostasis disorders are important links in the pathogenesis of burn disease. Burns of the IIIA degree, in which the epidermis and partially the dermis die in the wound [5,6], lead to local and systemic pathological changes, the development of severe dysmetabolic changes, microcirculation disorders, and inhibition of the body’s protective reactions. This requires the use of combination therapy [7,8,9]. Microwave therapy is actively developing and using portable devices that generate EMR with a noise spectrum evenly distributed in the frequency range of. The simplest way to achieve a therapeutic effect using MM and subMM EMR is to use sources with broadband frequency tuning or broadband sources
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