Study of the effect of fabrication conditions of porous gold electrodes on sensitivity of polymer-enzyme composite glucose sensors

Abstract

Porous structures can increase sensor electrode surface areas and therefore increase their sensitivity. However there are few studies revealing the relationship between different fabrication conditions of porous structures on gold electrodes and sensitivity of glucose sensors based on glucose oxidase. Here a variety of amperometric glucose sensor electrode fabrication conditions such as surface rebuilding time, rebuilding potential pulse and platinization time have been studied. The conclusions are as follows: First, the sensitivity of the sensors increased with surface rebuilding time as a result of the formation of porous structures. Second, that the rebuilding potential pulse between −3V and 5V applied to the electrodes resulted in a maximal sensitivity. Third, platinization can increase electrode sensitivity obviously, but overlong platinization time will lower the sensitivity instead. These results will be useful for the fabrication of high sensitivity glucose sensors.