Abstract
A study of the circular dichroism characteristics of various 16-substituted 20-keto pregnane and isopregnane derivatives has been made. The curves of the 16,17- trans compounds are simila to those of the 16-unsubstituted parent compounds. Modifications of functions in rings A and B have little effect, if any, on the circular dichroism maxima around 290 mμ. In the case of 16,17- cis compounds, both the configuration and the nature of the 16-substituent have an important bearing on the sign and intensity of the Cotton effect associated with the 17-acetyl side chain. The circular dichroism data for 16,17-epoxy-20-keto steroids are discussed.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
