Abstract

Rabbits were immunized with the supernatant of a homogenate of non-cancerous gastric mucosa to obtain an antiserum. This antiserum, after absorption by human jejunal mucosa and liver tissue, produced precipitin lines with the supernatants of homogenates of gastric carcinoma and gastric mu­ cosa. Fluorescent staining was attempted using this antiserum. Well-stained cytoplasms were ob­ served in cells of tissue imprints of normal gastric mucosa and gastric carcinoma. When frozen sec­ tions of peroperatively extirpated materials were likewise stained, the cells and the lumen of the glands were stained to a large extent in the non-cancerous gastric mucosa and tubulary adeno­ carcinoma of the non-scirrhous type. In scirrhous gastric carcinoma fluorescence-stained substances were scantly in the lumen of the glands but observable to some degree in the tumor stroma. It is suggested that infiltration of the interstitium by glandular antigens induces proliferation of stroma in gastric carcinoma.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.