Study of spectrum of inflammatory demyelinating disease of central nervous system

Abstract

We report the observations of twenty-five patients from Pune diagnosed with inflammatory demyelinating diseases of CNS over a period of 1 year. The aim is to highlight recent observations in inflammatory demyelinating diseases in the central nervous system. We emphasize the discriminative nature of new clinical, imaging, immunopathologic data, the rising incidence of anti-MOG antibody associated central nervous system demyelination and atypical MS due to easy and cost effective availability of anti-MOG antibody test. In the light of new findings, typical multiple sclerosis may represent a small entity in spectrum of demyelinating diseases.