Abstract
1. 1. Pubescent and prepubescent rats were injected with nephrotoxic serum in order to induce nephritis. 2. 2. Using Sephadex G 200 chromatography, we noted an exclused and a diffused fraction in each case, in normal and nephritic rat urines. A third peak appeared in pathological cases. 3. 3. Maximum absorbance of the 2 first peaks was unrelated with the total proteinuria which varied during the experimental disease course. 4. 4. Quantitative analysis of the total proteinemia and α-macroglobulins did not differ in normal and nephritic rat serum. We noted a diminution in albumin, β and γ globulins. Immunoelectrophoretical methods revealed a bifid precipitin line of the γ globulins. The presence of a pre-albumin in prepubescent rat serum lead us to suppose that Masugi nephritis symptoms are different according to the age of the rat.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Comparative Biochemistry and Physiology -- Part A: Physiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
