Study of some physiological parameters in renal failure patients with hepatitis C virus infection

Abstract

Renal failure is defined as the kidneys' inability to execute excretory functions, resulting in the retention of nitrogenous waste products in the blood. Therefore, the current study was aimed at detecting the hepatitis C virus in renal failure patients and investigating measurements of urea, creatinine, phosphorus, calcium and albumin. Also, Hb and ABO blood groups were investigated. In this study, 20 blood samples were collected from people aged (24–83) of both sexes and included (10) renal failure, (10) renal failure with hepatitis C and (10) controls aged (23–66). A highly significant increase (P<0.01) was observed in urea, creatinine and phosphorus levels in patients infected with renal failure without HCV and renal failure with hepatitis C virus infection groups in comparison to the control group. The other parameters albumin and hemoglobin concentration showed a highly significant decrease in renal failure patients with hepatitis C virus infection when compared to the healthy group. Calcium displayed a non-significant increase (P<0.05) in patients with renal failure without HCV when compared to renal failure with HCV infection. But albumin, urea and hemoglobin showed a nonsignificant decrease (P > 0.05) in patients with renal failure without hepatitis C infection when compared to those with renal failure. The ABO blood groups results for renal failure patients without hepatitis C virus infection showed the highest percent in the O+ blood group (60%) followed by A+, B+, AB+ and Arecorded as 10% for each one. The renal failure patient with hepatitis C virus infection group showed the highest percent of the O+ blood group (50%) followed by A+, B+, AB+ and A- recorded as (20%), (10%), (10%) and (10%) respectively.