Study of silicone hydrogel contact lenses’ surface reflection characteristics using confocal microscopy

Abstract

The physical and chemical properties of contact lenses (CLs) differ significantly from one another. This is already covered by the FDA classification, which divides soft lenses into groups and subgroups for additional characteristics. The differences relate to both the interior and surface of the lens. Several differences in the surface characteristics of individual contact lenses have been studied and demonstrated to date. However, one of their fundamental physical properties, that is light reflection or, quantitatively, reflectance has not been compared. This paper describes the surface differences of a range of silicone-hydrogel (SiHy) lenses using reflectance confocal microscopy. It shows the relationship between the amount of light reflected from the lens surface and the material parameters. Common SiHy lens materials were used in the study, including two lenses with surface modifications. Light incident at the interface between two media (phosphate-buffered saline and lens) with different refractive indices is partially reflected. The normalized results show significant differences between the reflection signals (1 vs 0.07), and that they are not correlated with the refractive index (R2 = 0.5536). For the water content (%H2O), a general trend was observed that the higher the %H2O, the lower the reflection signal is (R2 = 0.8105). The reflection signal and surface modulus show the best correlation. (R2 = 0.9883). The proposed CLs analysis method, using reflectance confocal microscopy, provides data to differentiate between lenses with and without surface modifications.