Abstract
Objective: The present study was undertaken to study the serum IgE levels in recurrent respiratorytract illnesses in children greater than 6 months to less than 5 years of age and to find thecorrelation between them. Methods: This was a prospective observational cross-sectional study. Thestudy was undertaken to determine the correlation of serum IgE levels with recurrent respiratorytract illness. A total of 99 children were included in this study. 2ml of blood was drawn by peripheralvenous phlebotomy in airtight screw-capped plastic vials for measuring serum IgE levels. The SerumIgE level is assessed by chemiluminescence. Results: Out of 99 children, 48 children had elevatedserum IgE levels and 51 had normal serum IgE levels. Serum IgE levels were significantly higher(66.07%) in males as compared to females (25.58%) with a p-value of 0.0003 (<0.05). Theelevation of serum IgE levels was 48.48% in all children (48 out of 99 children). It’s noticed that thenumber of children suffering from RRTI and the number of children with elevated serum IgE levelsincreased with increasing age. There is a significant increase in serum IgE levels from 10.00% ininfancy to 64.10% in the 49-60th month. Conclusion: This study showed an increasing number ofchildren with recurrent respiratory tract illness and serum IgE levels with increasing age. Males,preterm and bottle-fed babies are more prone. There was a significant role in a family history ofrecurrent respiratory tract illness in children with elevated serum IgE levels.
Highlights
Materials and methodsPediatric respiratory tract illness is one of the most common reasons for physician visits and hospitalization and is associated with significant morbidity and mortality
A total of 99 children were included in this study. 2ml of blood was drawn by peripheral venous phlebotomy in airtight screw-capped plastic vials for measuring serum IgE levels
This study showed an increasing number of children with recurrent respiratory tract illness and serum IgE levels with increasing age
Summary
Materials and methodsPediatric respiratory tract illness is one of the most common reasons for physician visits and hospitalization and is associated with significant morbidity and mortality. Respiratory illness (RI), mainly involving the upper airways, is common in children and their recurrence constitutes a demanding challenge for the pediatricians. It is necessary to discriminate between those with -managed causes for their symptoms such as recurrent viral infections or asthma, from the children with more serious underlying pathology such as bronchiectasis or immune dysfunction. Recurrent infectious rhinitis is usually defined as more than five episodes per year and recurrent pharyngitis or tonsillitis more than three episodes within 12 months. It is evident, that only a few appropriate tests are enough helpful to discriminate between a “well-being” child and a patient with immune dysfunction
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