Abstract
Organophosphate (OP) insecticides are the most probable common cause of acute poisonings in developing countries. OP intoxication often presents as medical emergencies, and its related morbidity and mortality have not decreased despite major advances in critical care.This study aims to determine the impact of serum amylase level for estimation of prognosis in patients with acute OP poisoning. Method: This prospective observational hospital-based study was performed on 100 patients with acute OP poisoning. Demographics data, clinical profile, serum amylase levels, complications,hospital stay and outcome were determined.Data were analyzed in the form of a frequency distributions using SPSS 26.0 version software.Result: Most patients were young adults with mean age of 29yrs ± 11yrs with slightly male predominance. Mean serum amylase level was significantly higher among patients with morbidity and mortality. Conclusion: Among patients with OP poisoning,higher serum amylase than normal was associated with severe clinical course and increased risk for mortality.Determination of serum amylase can be an effective marker of the prognosis and clinical course among OP poisoning patients.
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