Abstract
Dengue infection, an arthropod-borne viral hemorrhagic fever, continues to be a major challenge to public health, especially in South-East Asia. It has a wide geographical distribution and can present with a diverse clinical spectrum. The liver dysfunction could be a direct viral effect or an adverse consequence of dysregulated host immune response against the virus. Hepatic involvement can be characterized by manifestations of acute hepatitis, with pain in the right hypochondrium, hepatomegaly, jaundice, and raised aminotransferase levels. Several outbreaks of dengue infection have been reported from India. However, large clinical studies documenting hepatic involvement in dengue infection, especially in adults, are scarce.
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