Study of risk factors for lower extremity deep venous thrombosis in elderly patients with degenerative diseases of the spine

Abstract

Objective To explore the risk factors of lower extremity deep venous thrombosis (DVT) after orthopedic surgery in orthopedic patients. Methods We retrospectively analyzed 500 patients who underwent surgery in orthopedics due to degenerative diseases of the spine from September 2016 to May 2019. All patients underwent ultrasound examination of the lower extremities before surgery to confirm the absence of thrombosis Double lower extremity ultrasound on the 3th, 6th, 9th and 12th postoperative day. According to the results of ultrasound, the patients were divided into DVT group and non-DVT group. A total of 65 cases of DVT were diagnosed and the DVT formation rate was 13%. The age, D-dimer, body mass index (BMI), comorbidity, preoperative and postoperative coagulation, operation time, Logistic multivariate regression analysis of hospitalization time, intraoperative blood loss, etc. to explore risk factors associated with DVT. Results A total of 500 patients were included for analysis, According to the final results, 65 patients were included in the DVT group, and 435 were included in the non-DVT group. The incidence of DVT was 13%. Univariate analysis showed statistically significant differences in age, BMI, and hypertension between the two groups (P<0.05). Logistic regression analysis showed D-dimer [odds ratio (OR)=7.059, 95% confidence interval (CI)=2.864-17.401], OR=1.836, 95%CI=1.022-3.301) and operative time (OR=1.513, 95%CI= 1.039-2.203) is a risk factor for postoperative lower extremity DVT. Conclusion Obesity, D-dimer and long operation time are independent risk factors for lower extremity DVT. Key words: Spinal degenerative disease; Lower extremity deep venous thrombosis; Risk factor