Abstract
The neuro-immuno-cutaneous endocrine model explains the mind-body connection. This model explains how many inflammatory dermatoses are triggered or exacerbated by stress factors. These conditions are called psychophysiological skin diseases. Psoriasis is a common psychophysiological skin disease. It affects 2-4% of the population worldwide and involves multiple systems in the body. The rates of psychiatric comorbidities are high in psoriasis, but still, they are not given due attention which leads to an increase in morbidity and mortality in the long run. This study intends to uncover the psychiatric comorbidities in psoriasis patients. In this study, the prevalence of psychiatric disorders was investigated among 104 patients with psoriasis. Following rating scales were used; Hamilton rating scales for depression and anxiety, Presumptive stressful life event scale, Beck scale for suicidal ideation, and Dermatology life quality index. The prevalence of psychiatric disorders in Psoriasis patients was found to be 66.35%. Among the psychiatric disorders, 29.8 % were dependent on substances, 18.27% were found to be suffering from depression,15.38 % with anxiety disorder and 2.88 % with psychotic disorders. Psoriasis has a high prevalence of psychiatric morbidity.
Highlights
Psychodermatology or psychocutaneous medicine focuses on the relationship between psychiatry and dermatology, which deals with the study of the influence of psychosocial stress in the exacerbation and chronicity of skin illness.[1]
T-test and Chi-square test were applied to determine the association, where p-value less than 0.05 was considered statistically significant. This was a cross-sectional study where 104 patients with psoriasis were assessed for psychiatric disorders
In 37.5% of patients, psoriasis had a very large effect on the Quality Of Life (QOL), while in 20.2% of patients it had an extremely large effect on QOL (Table 3)
Summary
Psychodermatology or psychocutaneous medicine focuses on the relationship between psychiatry and dermatology, which deals with the study of the influence of psychosocial stress in the exacerbation and chronicity of skin illness.[1] Both physical agents and psychosocial stress factors are linked with the natural history of several skin diseases, psoriasis being one of them. Psoriasis is a chronic inflammatory autoimmune disorder that is associated with both genetic and environmental factors. It affects 2-4% of the population worldwide and involves multiple systems in the body.[2]. Most studies of the neuroendocrine response to stress in psoriasis have demonstrated a blunted HPA axis cortisol response and a heightened sympathetic response to a stressor.[2] Stress is a trigger and an exacerbating factor in the pathogenesis of psoriasis.[3]
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