Abstract
Background: The rising prevalence of overweight and obesity is associated with development of growing number of early complications in children and adolescents among that type 2 diabetes mellitus and metabolic syndrome (MS) is common. Present study has been designed to identify the prevalence of MS in children with overweight risk, overweight or obesity and to compare anthropometric and biochemical parameters in patients with metabolic syndrome and without MS.Methods: This is a cross sectional descriptive study conducted in the department of paediatrics where 120 patients with obesity were enrolled for this study and various metabolic parameters were compared.Results: In our study the prevalence of metabolic syndrome was 30% among obese and overweight children. Fasting insulin (18.65±13.64 mg/dl versus 16.48±10.32 mg/dl) was significantly higher in patients with MS than without MS (p is less than 0.05). Homeostatic model assessment of insulin resistance (HOMA-IR) was 5.84±1.43 in MS group and 4.54±1.34 in without MS group. The p value was 0.00. The glycocylated haemoglobin was significantly higher in MS group than without MS group (5.84±0.78 versus 4.54±0.34).Conclusions: From our study we can conclude that metabolic syndrome is a common problem in children with overweight and obesity in our region. Insulin resistance and metabolic abnormality were more common in children with MS.
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