Abstract
The Sayat-sayat(LeersiahexandraSw) plant is a plant used in traditional medicine by the Batak Karo people in North Sumatra. This study aims to examine the phytochemical content, antibacterial activity and cytotoxic test of acetone extract of L.hexandraSw seeds. Phytochemical tests include tests for alkaloids, flavonoids, saponins, tannins and steroids. Antibacterial tests were carried out against Propionibacterium acnesATCC (27853), Escherichia coli ATCC 25922, Bacillus cereus ATCC 1178, Salmonella enterica ATCC 14028 with the paper disc diffusion method M02-A11 (CLSI) and continued with the determination of MIC and MBC using the microdilution method M07-A9 (CLSI). The toxicity test used the Brint Shrimp Lethality Toxicity (BSLT) method using Artemia Salina Leach shrimp larvae. The results of phytochemical screening showed that the acetone extract of the L.hexandraSw seeds contained alkaloids, flavonoids and terpenoids. The results of the antibacterial activity test showed the best activity against B. cereus ATCC 1178 and S. enterica ATCC 14028 with an inhibition zone in the range of 8.4-8.6mm, with MIC and MBC values of 625 μg/mL. The results of the toxicity test are toxic and potentially bioactive.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.