Abstract
Hydrogen titanate nanotubes were synthesized by hydrothermal process using 10 M NaOH and TiO2 anatase powder. The material synthesized was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) to ensure the structural and morphological characteristics. The interaction of calf thymus DNA (CT-DNA) and bovine serum albumin protein with suspended aqueous solution of titanate nanotubes was investigated using UV absorption spectroscopy and the apparent association constant was found to be, Kb= 1.68 × 104 M-1 and Kap=5.41 × 103 M-1 for DNA and BSA respectively. Addition of the titanate nano material resulted quenching of fluorescence spectra of ethidium bromide-DNA in tris HCl buffer solution and that of aqueous protein solution. The apparent binding constant (Ksv= 5.46 × 104M-1 for DNA binding and Ksv = 6.063 × 103M-1 for protein binding) was deduced from relevant fluorescence quenching data using Stern-Volmer equation.
Highlights
One-dimensional nanostructures have drawn a great attention due to their potential applications in a variety of novel devices in recent past [1,2,3,4,5]
Titanate nanotubes of nearly 8 nm in diameter were first reported by Kasuga and co-workers, employing a hydrothermal treatment of rutile TiO2 powders in strong aqueous solution of NaOH at 110 ̊C followed by HCl washing [10]
Chen et al concluded that these nanotubes were of H2Ti3O7 structure based on diffraction and high-resolution transmission electron microscopy (HRTEM) results [11]
Summary
One-dimensional nanostructures have drawn a great attention due to their potential applications in a variety of novel devices in recent past [1,2,3,4,5]. Several efforts were made to synthesize nanorods and nanowires of more complex structure and conesquently a number of one-dimensional nanomaterials including metals, oxides and nitrides have been reported. TiO2 nanoparticles are acting as biosensors in chemical and biochemical fields and their applications are becoming more extensive. These probes have been applied to the ultrasensitive detection of proteins, DNA sequencing, clinical diagnostics, etc. Titanate nanotubes of nearly 8 nm in diameter were first reported by Kasuga and co-workers, employing a hydrothermal treatment of rutile TiO2 powders in strong aqueous solution of NaOH at 110 ̊C followed by HCl washing [10]. Chen et al concluded that these nanotubes were of H2Ti3O7 structure based on diffraction and high-resolution transmission electron microscopy (HRTEM) results [11]
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