STUDY OF NEUTROPHIL-LYMPHOCYTE RATIO , PLATELET-LYMPHOCYTE RATIO AND MEAN PLATELET VOLUME IN CRP POSITIVE AND CRP NEGATIVE PATIENTS OF RHEUMATOID ARTHRITIS.

Abstract

Aim – To study the Comparison of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and mean platelet volume in C-Reactive Protien positive and C-Reactive Protien negative patients of Rheumatoid arthritis. Material And Methods –A cross-sectional, prospective and observational study was conducted at MLN Medical College, Prayagraj. A total of 60 patients of rheumatoid arthritis were enrolled in the study with appropriate inclusion and exclusion criterias. Result – Out of 60 rheumatoid arthritis patient 50 had positive CRP and 10 patients had negative CRP. The mean NLR of CRP positive patients were 3.07 and for CRP negative patients were 2.74. The mean PLR of CRP positive and negative patients were 2.61 and 2.74 respectively and mean MPV of CRP positive patients were 8.43 and for CRP negative were 8.76. Conclusion– Inammatory markers such as the CRP was positive in majority of patients. NLR showed positive while PLR and MPV showed negative correlation with CRP positivity. All of these relationship were statistically not signicant with CRP