STUDY OF MULTIDRUG RESISTANT ACINETOBACTER IN INTENSIVE CARE UNIT (ICU) PATIENTS.

Abstract

Introduction- Acinetobacter had gained increasing attention as a nosocomial pathogen causing severe, life-threatening hospital infections, especially in intensive care units (ICUs). It is notorious to develop multi drug resistant. Management of multidrug-resistant Acinetobacter spp. infections is a great challenge for physicians and clinical microbiologists. This study was designed to study the various species ofObjectives: Acinetobacter prevalence and antibiotic susceptibility patterns of Acinetobacter sp. as isolated from patients lodged in intensive care units (ICUs) of a tertiary care hospital in central India. The study was carried out in microbiology laboratory of a tertiary care hospitalMaterial & methods: from July 2018 to July 2020. Samples were collected, processed and Acinetobacter isolates were identied by standard microbiological procedures. Antimicrobial susceptibility testing performed by kirby-bauer disc diffusion method as per CLSI guidelines. Out of total 200Results: isolates of Acinetobacter, ACB complex 189 (94.5%) was found to be the most common species isolated. Maximum isolates were obtained from medicine intensive care unit. The most common infection was found to be pneumonia. Maximum isolates were resistant to Cetriaxone, Ceftazidime, Ciprooxacin etc and least resistance was seen in Imepenem, Piperacillin-Tazobactum, Amikacin,. All the strains were sensitive to Colistin. Acinetobacter has emerged as an important nosocomial pathogen showing high degree of resistance to most antimicrobials.Conclusion: Early identication and continued surveillance of their antibiogram is essential for preventing the spread of Acinetobacter in hospital environment.