Study of Liver Function Tests and Renal Function Tests in diabetic type II patients

Abstract

In individuals who have diabetes type 2, they are a higher incidence of liver function test abnormalities than individuals who do not have diabetes. The most common liver function tests ( LFTs) include the serum aminotransferases, alkaline phosphatase, bilirubin, albumin, and prothrombin time. Aminotransferases, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST), measure the concentration of intracellular hepatic enzymes that have leaked into the circulation and serve as a marker of hepatocyte injury. The study was done on (55) blood samples which divided in two groups: first group was (40) the patients (diabetic typeII ) (25 females &15 males) and the second was (15) the control group which( 8 females &7 males) , glucose , Urea, Creatinine, Alkaline phosphates ,ALT and AST were measured in these groups. there is no significant difference between females and males in controls and patients, there is significant difference between the controls group and the patients and the correlation between the glucose and biochemical parameters in female patients was glucose levels were positive significant correlated with Creatinine, Alkaline phosphate, ALT and AST, but non- significant with Urea, but In males the correlation between the glucose and all biochemical parameters even Urea. As conclusions there is relationship between the glucose and biochemical parameters above .