Abstract
Three groups of subjects have been divided (25/group): healthy normotensive non-pregnant women (Group A), normal normotensive pregnant women (Group B), and women with preeclampsia (Group C).The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin , creatinine , blood urea nitrogen, triglyceride , total cholesterol and glucose have been estimated in all subjects. All measured parameters were determined by spectrophotometric analysis. The results showed a significant(P
Highlights
Three groups of subjects have been divided (25/group): healthy normotensive non-pregnant women (Group A), normal normotensive pregnant women (Group B), and women with preeclampsia (Group C).The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin, creatinine, blood urea nitrogen, triglyceride, total cholesterol and glucose have been estimated in all subjects
Several studies have shown that women with preeclampsia have cardiovascular risk profiles in pregnancy associated with levels of serum lipids and blood pressure
It is important to identify women who are at high risk of developing the disease early in pregnancy. This is because early identification of biochemical markers of the disease would facilitate selective recruiting of those at increased risk for preeclampsia and to help in determining those patients who were more likely to benefit from interventional measures should a therapeutic intervention prove successful[7.8,9]
Summary
Three groups of women (25 / group) have been selected for the study. The age of the women was between 18 – 35 years. All women of group (B) and (C) were in the third trimester of pregnancy. The preeclamptic women were diagnosed by the presence of persistent hypertension (more than or equal 140 / 90 mmHg), gross proteinuria (tested by heat test of urine) and pathological oedema. Blood samples have been drawn from all the subjects following a fast of 12 hours. The blood was transferred to a plain tubes allowed to. Vol.9(2)2012 stand at room temperature for 10 minutes to permit clot formation. After centrifugation for 15 minutes at 300.
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