Abstract
Thin films of ZrO 2 and hydroxyapatite/ZrO 2 were created by excimer laser ablation on Ti6Al4V substrates. ZrO 2 layers were fabricated in vacuum by KrF laser at various substrate temperatures and hydroxyapatite (HA) layers were fabricated in water vapor ambient by ArF laser and in water vapor/argon ambient by KrF excimer laser. Film properties were evaluated by XRD, SEM and WDX methods. The test of mechanical adhesion was proceeded on ZrO 2 films. XRD analysis proved the presence of amorphous or crystalline HA in the deposited films. SEM method demonstrated smooth surface covered by droplets for both HA and ZrO 2 films. Ca/P ratio of the HA films is higher than that of the natural HA and is within the range of 2.8–3.0. The HA/ZrO 2 and ZrO 2 samples were tested in vitro for cytotoxicity. The best results were received by the HA/ZrO 2 samples in the test of cytotoxicity. Fibroblasts cultivating with HA/ZrO 2 samples exhibited subconfluent and confluent growth and showed fibronectin homogenously.
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