Abstract
It is shown with 1-ethoxyisoindolenine that the reaction of lactim ethers with α-amino-α-cyanoacetamide also extends to partly aromatized lactim ethers, although these react much less readily. Condensation of 1-ethoxyisoindolenine with α-amino-cyanoacetamide gives 4-carbamido-5-aminoimidazo[1, 2-1′, 2′]isoindoline, from which a new series of purinoisoindioline derivatives is synthesized. Authors: R. G. Glushkov, O. Yu. Magidson. English Translation in Chemistry of Heterocyclic Compounds , 1965, 1 (1), pp 57-59 http://link.springer.com/article/10.1007/BF01168921
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