Abstract

The observation that marked skin changes develop in rats suffering from the unsaturated fatty acid deficiency disease described by Burr and Burr1 suggested the possibility that certain dermatological disorders of childhood, such as infantile eczema, might be dependent in part at least upon this type of dietary deficiency. A few preliminary observations on eczematous babies given liberal supplements of unsaturated fatty acids in their diets in addition to the routine treatment were sufficiently encouraging to suggest the desirability of careful study of the blood lipids in this disease. In order to determine whether any relationship might exist between the two clinical entities, similar blood studies were undertaken on eczematous infants and on rats suffering from the unsaturated fatty acid deficiency.The present paper deals exclusively with the results in the cases of infantile eczema. The total iodine absorption of the serum was first determined on one or more occasions in 10 cases of eczema and in 16 no...

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