Abstract
Thirteen field (wild) isolates of type 2 poliovirus have been tested for a number of characteristics, and with minor exceptions they have fallen into two groups. One group is characterized by poor neutralizability when the immune serum was included into the agar overlay (Weeker's technique); they were highly virulent for monkeys, multiplied well at low concentrations of sodium bicarbonate and at low osmotic pressure, multiplied fairly well at 41°, were thermostable, resistant to interference effects and to certain tissue extracts, and multiplied well with limited oxygen supply. The other group had the opposing characteristics for all these markers.
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