Abstract
Introduction: Hematological parameters are very useful profiles in the effective management of the disease However, there is scarcity of studies on the hematological parameters of SCD in Gujarat.
 Objective: The objective of the study was to changes in hematological finding in patients of sickle cell disease.
 Materials and Methods: This Prospective studyincludes total 150 participants who suffering from sickle cell anemia and attending at our Institute Complete blood count (CBC) and sickling test was done from all participants Comparison of results was done between Sickle cell trait and Sickle cell disease Group.
 Results: The mean age of the SCA patients was 25 54±10 years. Maximum participants are found to be from age group 25-30 yr(n=35) followed by 20-25 yr(n=30) of the 150 SCA patients, 89 (59 33%), and 61 (40 6%) were males and females, respectively. The Mean value of WBC count(/cumm) in SCT group is10611±3015 and SCD is 14427±3693 while the Mean value of Platelet count (lacs/cumm) is 3.75±1 i10 and 4 04±0 94 SCT and SCD Group.
 Conclusions: The present study found elevated levels of WBC and PLT among the SCD patients, possibly reflecting spleen effect in these patientsi These hematological parameters present a more descriptive data on SCD patients in Gujarat and may as well provide a useful tool and assist clinicians in the management of SCD patients in india.
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