Abstract
Methods HIV-positive patients attending the Antiretroviral Therapy Centre, at CSM Medical University, Lucknow, India, who were to be initiated on ART according to clinical and immunological criteria, were screened for the presence of asymptomatic abdominal lymphadenopathy by ultrasound. Fifty patients were included in the study. They had no overt evidence of tuberculosis, malignancy, lymphoma, or atypical mycobacterium infection attributable to the enlarged abdominal lymph nodes. Ratio of males to females was 2:1, mean age of presentation was 32.5 yrs and mean CD4 count was 126/cmm. The patients were followed by repeat CD4 count (at 3 months) and clinically (monthly) for the development of IRIS and clinical progression.
Highlights
HIV-positive patients attending the Antiretroviral Therapy Centre, at CSM Medical University, Lucknow, India, who were to be initiated on ART according to clinical and immunological criteria, were screened for the presence of asymptomatic abdominal lymphadenopathy by ultrasound
It was observed that those patients with an initial low CD4 count and good response to ART had a greater incidence of Immune Reconstitution Inflammatory Syndrome (IRIS)
We conclude that IRIS is common in Indian HIV-positive patients on ART, those who have low CD4 count
Summary
Address: CSM Medical University, Lucknow, India * Corresponding author from Ninth International Congress on Drug Therapy in HIV Infection Glasgow, UK. 9–13 November 2008. Address: CSM Medical University, Lucknow, India * Corresponding author from Ninth International Congress on Drug Therapy in HIV Infection Glasgow, UK. Published: 10 November 2008 Journal of the International AIDS Society 2008, 11(Suppl 1):P158 doi:10.1186/1758-2652-11-S1-P158. Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1758-2652-11-S1-info.pdf
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