Study of Histopathological and Hematological Effects of Cysteine Added to The Broiler Diet contaminated With Aflatoxin B1

Abstract

In this project, 270 broiler chickens one day old were used to demonstrate the effect of the addition of the amino acid cysteine ​​added to the diets of birds contaminated with aflatoxin B1 on the liver and kidneys. The experiment was divided into 9 equal groups; & each group had 30 birds with 3 replicates, and each replicate had 10 birds. The control group was without addition. As for the treated groups, cysteine, ​​and aflatoxin B1 were added to their diets at 40%, 80% & 160% cysteine, and aflatoxin B1 was added at 0 ml, 4 ml & 8 ml, respectively. The variables collected were liver & kidney histopathology, Alanine aminotransferase (ALT), and Aspartate aminotransferase (AST) levels. When adding cysteine to a bird's diet contains Aflatoxin B1 not observed in blood ALT amount. The histopathological examination showed fibrosis in the liver and degeneration and dilatation of cortical tubules in the kidney. The amount of AST in the blood was greater at 28 days of age, specifically in G2 (Cysteine 80%) &G3 (Cysteine 160%) at Aflatoxin B1 0 ml, which caused significant damage to the liver. The giving of cysteine 40, 80& 160% in birds' feed contaminated with AflatoxinB1 0, 4& 8ml, which is intake by birds, has harmful effects on the health of the liver.