Study of histomorphological patterns of ovarian tumors

Abstract

Introduction: Ovarian tumors have various histomorphological patterns. Histopathological examination plays an important role is classifying ovarian tumors for better prognosis. Ovarian tumors are classified into surface epithelial tumors, germ tumors and sex cord stromal tumors. This study was done to know various histomorphological patterns of ovarian tumors. Materials and Methods: Both retrospective and prospective study done from March 2013 to April 2015 for 2 yrs in the department of pathology, Kakatiya Medical College Warangal and private histopathological laboratories. On microscopy histomorphological patterns of ovarian tumors were noted. Sections were given and slides were stained with H & E. Special stains like reticulin, PAS, mucicarmine were done where ever necessary. Results: 154 ovarian tumors were studied, 78.5% (121/154) were benign and 21.4% (33/154) were malignant. Surface epithelial tumors were most common (61.6%), followed by germ cell tumors (29.8%). Sex cord stromal tumors comprised only 4.5 % (7/154) of all ovarian tumors. Metastatic tumors of ovaries were far less common than primary ovarian tumors. They comprised only 3.8 % (6/154) of all ovarian tumors. Age ranged from 15-65 with majority of cases were reported among 35- 45yrs 81 (52.5%). The youngest patient of our series was a girl of 16 yrs with dysgerminoma and the oldest patient was a 65 yrs, a case of mucinous cystadenocarcinoma ovary. Conclusion: Surface epithelial tumors were most common followed by germ cell tumors. Majority of tumors were reported amongage group 35- 45yrs. Metastatic tumors of ovaries were less common.