Study of hamartomatous lesions along with its fatality with review of literature

Abstract

Albrecht introduced the concept of hamartoma at the beginning of twentieth century to designate a tumor like or non-neoplastic malformation or inborn error of tissue development. They arise virtually in all organs. They may derive from any three germinal layer of which mesodermal derived overgrowth is most common. They are slow growing and have self-limited growth. The formation of these growth take place by abnormal mixing of tissue in course of development. Present retrospective study was conducted in pathology department over a period of 2 years from July 2020 to June 2022. Total twenty cases were included in study and it was observed that twelve cases occurred in head and neck region, one case occurred over chest, one case in gastrointestinal tract and six cases in extremities. It is important to differentiate hamartomas from related lesions like choristoma, teratoma and benign tumors to avoid aggressive treatment.