Abstract
Background: Peritonitis caused by gastrointestinal perforation is one of the most prevalent surgical emergencies worldwide. Early detection and treatment of Perforation Peritonitis may significantly minimize morbidity and death. The result is improved by surgical treatment and good perioperative care. The purpose of this clinical trial is to assess the outcome of perforation peritonitis. Hence the present study was conducted at a tertiary healthcare institute to study factors involved in perforative peritonitis and its significance to mortality and morbidity.
 Materials and Methods: It was a Prospective Observational Study, conducted over a period of 18 months at the department of General Surgery, KIMSDU, Karad, among the patients presenting in emergency room of Krishna Institute of Medical Sciences and Research Centre, Karad, between any age group, with symptoms of acute pain in abdomen with gas under diaphragm seen on either chest radiograph or x-ray erect abdomen.
 Results: In the present study we assessed the Operative procedures among the study subjects. We observed that open appendectomy was performed among 23.08% study subjects, open perforation closure was performed among 26.92% study subjects, resection and anastomosis was performed among 8.46% study subjects, resection anastomosis and Stomy was performed among 6.92% study subjects, simple closure was performed among 34.62% study subjects.
 Conclusions: All the MPI parameters: extension of peritonitis, presence of organ failure, time of presentation, type of exudates, presence of malignancy, age, found to be associated with severity of peritonitis.
Highlights
Peritonitis caused by gastrointestinal perforation is one of the most prevalent surgical emergencies worldwide
We observed that majority of the study subjects belonged to the age group of 46 to 55 years (31.54%), followed by 36 to 45 years (24.62%), more than 66 years among 29.69% study subjects
We observed that majority of the subjects presented with duration of 4 to 6 days (47.69%), followed by more than 7 days among 42.31% subjects. 10% study subjects presented with less than 3 days
Summary
Peritonitis caused by gastrointestinal perforation is one of the most prevalent surgical emergencies worldwide. Detection and treatment of Perforation Peritonitis may significantly minimise morbidity and death. It has been well documented that the majority of perforated peritonitis patients in our subcontinent appear late These patients have well-established widespread peritonitis with purulent faecal pollution and septicemia, increasing the risk of morbidity and death and complicating the challenge of providing appropriate perioperative care [4]. Detection and treatment of Perforation Peritonitis may significantly minimize morbidity and death. The result is improved by surgical treatment and good perioperative care The purpose of this clinical trial is to assess the outcome of perforation peritonitis. The present study was conducted at a tertiary healthcare institute to study factors involved in perforative peritonitis and its significance to mortality and morbidity. We observed that open appendectomy was performed among 23.08% study subjects, open perforation closure was performed among 26.92% study subjects, resection and anastomosis was performed among 8.46% study subjects, resection anastomosis and Stomy was performed among 6.92% study subjects, simple closure was performed among 34.62% study subjects
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