Abstract
Recently, 1-phenyl-3-methyl-5-pyrazolone (PMP) 9 and its methoxy analog, 1-(p-methoxy)-phenyl-3-methyl-5-pyrazolone (PMPMP) 10 have been used for pre-column derivatization of carbohydrates. The nucleophilic activity of these compounds is well known. 11,12 The electrochemical synthesis of organic compounds is a wellestablished technique and has been widely implemented for syntheses ofmaterialsthatarenotaccessiblebyconventionalmethods. 5 Electrochemical methods for the synthesis of organic compounds are green methods that utilize environmentally friendly solvents, a great advantage of these methods. 13 In addition, it is possible to monitor the synthesis process by electrochemical methods. 14 In the present work electrochemical activity of catechol compounds was studied in the presence of 1-phenyl-3-methyl-5pyrazolone as a nucleophile and the reaction mechanism was monitored by means of cyclic voltammetry and controlled-potential coulometry. The products were synthesized by an electrochemical method and characterized by means of FT-IR, 1 HNMR, 13 CNMR, MS spectroscopy and elemental analysis. The products were obtained in good yields and high purity. Theses materials might be used as analgesics in medical applications. 15
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