Study of E. coli Pathogens Causing Intestinal Infections and Use of Bacteriophage Preparation-Coli Phage

Taras Gabisonia,Robert Mirzikashvili,Irakli Chkhetia,Maia Zarnadze,Teimuraz Beridze,Mariam Pkhaladze,Giorgi Gabisonia,Natia Tamarashvili,Nino Kekenadze,Mariam Lomidze,Manana Loladze

doi:10.36648/1989-8436.11.1.99

Abstract

According to the data of World Health Organization (WHO) about 2 billion of people get sick with intestinal infections annually. The pathogens which spread through food and water are the main causes of the sickness and mortality; they lead to death of about 1.8 million each year. Resulting from the mentioned problem, it carries particular importance to conduct microbiological and molecular research of bacterial pathogens causing intestinal infections. One of the main pathogens, which spread through waters, is variety of Salmonella, pathogenically Escherichia coli and Shigella. Monitoring the food and water related pathogens would facilitate the process of downsizing their frequency in the environment, which on its own would reduce the risk of spreading diseases caused by the mentioned pathogen amongst humans. Early identification of these pathogens has the vital importance for quick and effective treatment.

Highlights

Given the specific resistance of bacterial strains to antibiotics, the determination of sensibility to antimicrobial drugs is very important for the monitoring of pathogens and may be used as a necessary epidemiological marker for mentioned bacteria [1,2,3,4]
To reach out the defined objectives and aims, in frames of the project we have communicated with clinical laboratory, from there we received strains of the E. coli derived from the patients
From the Bacteriological Laboratory of the clinical we were given-56 pathogenic strain of E. coli

Summary

Introduction

Given the specific resistance of bacterial strains to antibiotics, the determination of sensibility to antimicrobial drugs is very important for the monitoring of pathogens and may be used as a necessary epidemiological marker for mentioned bacteria [1,2,3,4]. Medications, treatment of the infectious diseases gains more and more problematic characteristics. The reason for this is the fact that throughout the time there have been produced strains of bacteria, which are stable, selective and resistant towards various medication, in the nature. The latter fact has significantly reduced effects of many antibiotics, Sulfanilamide and of other medicines used for treatment, in some cases they even got useless. To determine sensibility of pathogenic strains towards this medicine

Materials and Methods

Results and Discussion

Conclusion