Abstract

In newer times, great advances has been made by the discovery of the newer products from the natural sources. Towards the growing awareness in the treatment of the human degenerative disorders, polyphenols comes into play. Polyphenols are bioactive compounds that are commonly evacuated from natural, synthetic and semi-synthetic sources. They have a collective functions like antimicrobial properties and free radical scavenging activity. Polyphenols has an additional ability to reduce the oxidative damage of various compounds such as carbohydrates, lipids proteins etc. They mainly occurs as glycosides and are combined with varying organic acids. These glycosides helps in combating against the aggressive pathogenic organisms. They are found in a mixed state naturally. The natural polyphenols exemplifies a novel and relevant strategy in the treatment of human degenerative disorders. They play an important role by promoting the growth of Bifidobacterium sp. in the human GI tract this bacteria reduces the pH in the intestinal area and henceforth provides protection there. There are certain metabolic products of polyphenols that are demarked separately as they provide improvised actions against IBD patients. The herbal polyphenols gets hydrolysed through the intestinal brush border cells and thereby able to reduce the enzyme produced toxicity. This property shows a promising characteristic of the polyphenols that has the ability of modulating the human gut micro flora and enhancing certain friendly mechanisms within. On the line parallel to this, focus will also be on other human degenerative disorders that can be prevented by the action of the polyphenols.

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