Abstract
Abstract This paper evaluates possible relations between the clinical activity and the histopathological findings of the entire intestine in dogs with inflammatory bowel disease (IBD). To perform this study, hospital records of 64 dogs of different sex and breed diagnosed with IBD were evaluated. The results of this study did not show a statistically significant correlation between clinical activity and the histopathological assessment of dogs with IBD. Certain connections were found between diarrhea and lacteal dilation in duodenum, and hematochezia and villous epithelial injury in colon but no other associations were found between the rest of the lesions and symptoms.
Highlights
Canine inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder of unknown cause and ill-defined pathogenesis (1)
Clinical signs and histological lesions of 64 animals of different breed and sex with IBD are showed in Tables 3a, b and in Tables 4a, b
The histopathologic scoring system used in this study provided important information on the extent of mucosal inflammation in the GI tract of dogs with IBD
Summary
Canine inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder of unknown cause and ill-defined pathogenesis (1). Even with standardized grading schemes, most studies do not support a correlation between the severity of clinical signs and histological score since findings interpretation may vary widely between pathologists (10, 13). Despite this fact, the numeric index generated by some of these methods has been used to help clinicians and researchers to correlate inflammatory lesions with clinical signs (1). Jergens et al (1) proposed a set of assessment criteria called the Canine Inflammatory Bowel Disease Activity Index (CIBDAI) The suitability of this index as a monitoring tool is determined by the correlation between the clinical index and the histopathological lesions (1)
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