Abstract
Background: The completesyndrome of diabetes mellitus,related metabolic aberrations anddiabetic complications is posing a major threat in the 21st century. Cognitive dysfunction is a well known complication of diabetes which continues to be investigated. Aims and Objectives: To evaluate the cognitive functions using electrophysiological (P300 latencies) tests in diabetics and non diabetics in the age group of 40 - 59 years with same gender proportion, to analyze whether cognition is affected in diabetics when compared to non diabetics and to know the usefulness of electrophysiological (P300latencies) tests in detecting subtle cognitive changes. Materials and Method: The study was conducted on 50 diabetics and 50 non diabetics aged between 40 and 59 years. Cognition was assessed using P300 potential.The evoked potential data analysis was done using Student unpaired T test to compare the mean of two groups. Results: The absolute peak latencies of P3 component of endogenous cognitive evoked potentials was significantly prolonged among diabetics (334.8 + 20.8) as compared to controls (285.7 + 14.9). There was no statistically significant difference between groups when analyzed for N2 in Czand Fz. Conclusion: This study identifies prevalence of cognitive dysfunction in diabetic patients when assessed using electrophysiological tests.Good cognitive function is critical to safely manage diabetesand draws attention to various challenges in their management. Clinicians should consider screening for cognitive function in diabetics using P300, as it is effective in detecting subtle changes much before their clinical manifestation.
Highlights
Diabetes mellitus (DM) is taking its place as a main threat to human health in the 21st century
Clinicians should consider screening for cognitive function in diabetics using P300, as it is effective in detecting subtle changes much before their clinical manifestation
The study was conducted among diabetics and non diabetics to find out relationship between diabetes and cognition, in the age group of 40-59 years.The data was analyzed by using SPSS 18 and excel was used to generate graphs, tables etc
Summary
Diabetes mellitus (DM) is taking its place as a main threat to human health in the 21st century. The number of people with DM worldwide has increased more than two fold over the past three decades. In 2011, approximately 366 million people worldwide had DM, 90% of whom had type 2 DM. The number of people globally with DM is estimated to be 552 million (87 million in India) by 2030, which will represent. 80% cases of DM live in less developed countries.3DM is known to have devastating complications on multiple organs in the body. The completesyndrome of diabetes mellitus,related metabolic aberrations anddiabetic complications is posing a major threat in the 21st century. Cognitive dysfunction is a well known complication of diabetes which continues to be investigated
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
