Abstract
Abstract Cobalt has been estimated in plasma, liver, urine, hair and nails in 10 ICC patients and equal number of controls by carbon rod atomization. Cobalt level in ICC and controls was: liver tissue 0.01–0.16 (0.09 + or − 0.03) and 0.02–0.13 (0.08 + or − 0.03) μg Co/g wet wt; hair 0.01–0.16 (0.09 + or − 0.03) and 0.01–0.21 (0.07 + or − 0.05) μg Co/g; nails 0.04–0.25 (0.12 + or − 0.06) and 0.06 — 0.36 (0.14 + or − 0.04) μg Co/g; plasma 0.1–0.8 (0.4 + or − 0.2) and 0.1–0.6 (0.3 + or − 0.1) μg Co/dl; urine 0.1–2.7 (1.7 + or − 0.4) and 0.4–2.5 (1.2 t or − 0.4) μg Co/24 h, respectively. There was no significant difference (p = NS) in cobalt level in plasma, urine, liver tissue, hair and nails between ICC patients and controls. Large dose of vitamin B12 has been recommended and prescribed at many centres for the treatment of ICC, has no therapeutic base since cyanocabalamine contain a central cobalt atom and cobalt level is unchanged in ICC.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
