STUDY OF CLINICAL PROFILE OF PATIENTS OF NON ALCOHOLIC FATTY LIVER DISEASE AND ITS ASSOCIATION WITH METABOLIC SYNDROME

Abstract

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver problems in the western world. It is known to be associated with various metabolic abnormalities, but not much information regarding association between the metabolic disease and the severity of fatty liver is available. We conducted a study on 100 consecutive patients aged >18 years attending the outpatient and inpatient Department of General Medicine, Rajarajeswari Medical College and Hospital according to the inclusion and exclusion criteria. The study was an observational and analytical study of patients diagnosed as NAFLD. All patients diagnosed as NAFLD were investigated for metabolic syndrome according to the NCEP ATP III criteria and a relationship between NAFLD and metabolic syndrome was studied. We found that 53% of the patients of NAFLD had metabolic syndrome and statistical signicance was found in waist circumference, blood pressure, triglycerides, and fasting glucose. Its early detection will help CONCLUSION: in modifying the disease course, delaying complications and will also play a major role in preventive cardiology. It has been observed that there is high prevalence of all the components of metabolic syndrome in cases of NAFLD