Abstract
Background: Advances in the management of breast cancer led to significant improvement in survival. This has led to an increased incidence of Loco-Regional Recurrences. Objective: To report clinical outcome of patients presenting with locoregional recurrence (LRR). Material and Methods: The present prospective observational study was done at Tata Memorial Hospital, Mumbai and Advanced Center for Treatment and Education of Cancer, Navi Mumbai. A total of 100 consecutive patients of local/ regional/ Loco-regional recurrences and fulfilling the study inclusion criteria were invited to participate in this study. Statistical analysis was done using SPSS Statistics version 20.0. Survival period was defined as the period from the date of diagnosis to the development of recurrence or to the date of the last recorded clinical followup.Results: The mean and median overall survival from the time of diagnosis of primary for the entire group was 62.8 and 41.2 months (range 8.0-237.5) respectively. The mean and median disease-free survival was 53.9 and 32.7 months (range 0.33-23.3) respectively from the date of primary diagnosis. Conclusion: Multi-modal therapy comprising of optimal locoregional treatment and systemic therapy achieves durable local control.
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