Abstract
Introduction: Diabetes results from hyperglycemia and improper glucose, lipid, and protein metabolism. The elderly population will quadruple in 10 years. LMICs have the highest type 2 DM patients. Insulin resistance and beta cell abnormalities cause T2DM. This study compared HbA1c, FPG, and lipids to controls. Materials and methods: The study was carried out in the Department of Biochemistry L.LRM Medical College, Meerut. The study was done on 250 individuals, who included 100 uncontrolled type-2 diabetic (Group III), 100 controlled type-2 diabetic (Group II) and 50 healthy individuals (Group I). Blood biochemistry and immunology for various parameters such as Fasting Blood Sugar (FBS), Glycosylated haemoglobin (HbA1c), Total Cholesterol (TC), Triglyceride (TG), High density-lipoprotein cholesterol (HDL-c), Low density lipoprotein cholesterol (LDL-c), Very low density lipoprotein cholesterol (VLDL-c), Urea, Creatinine were carried out for all three groups. SPSS16.0 was used to analyse the results. Results: In our study we found highly significant increase (P< 0.001) of fasting blood sugar and glycosylated hemoglobin levels in group II and group III as compared to group I. In the present study, the patterns of lipid profile parameters in type-2 diabetic subjects were also studied.
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