Abstract

In the present study, the biomaterial specimen derived from a farm animal with a chronic reproductive system infection was carefully investigated using the Next Generation Sequencing method. The bacterial DNA of the genus Enterobacter was detected. The genetic determinants of resistance to 12 classes of antibiotics were identified in the genome of this microorganism. The data obtained highlight the necessity of strengthening global control over the spread of resistant microorganism strains in agriculture especially in the animal husbandry sector.

Highlights

  • Infectious diseases of farm animals are an urgent problem in the field of animal husbandry

  • Analysis of short sequences with metagenomic approaches made it possible to detect in the clinical sample the presence of DNA which was taxonomically associated with opportunistic microorganisms of the Enterobacteriaceae family

  • According to the reports [9,10], drug-resistant variants are most common among the Enterobacter genus

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Summary

Introduction

Infectious diseases of farm animals are an urgent problem in the field of animal husbandry. Infections causing different pathological processes in the reproductive system of animals may reduce the productiveness and productivity of livestock, resulting in significant damage and loss to agribusiness. According to the reports on the epizootic situation with animal infection diseases in the Russian Federation (https://fsvps.gov.ru/fsvps/iac/rf/reports.html), cases of bacterial infectious diseases associated with reproductive system pathologies are annually registered on the territory of the Russian Federation. The annual increase in the number of bacterial strains capable of exhibiting resistance to the main classes of antibiotics leads to a fatal decrease in the spectrum of drugs for the effective therapy of infectious diseases in farm animals [3,4,5,6]

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