Study of Antimicrobial Resistance among Enterococcus Species in Tertiary Care Teaching Hospital

Abstract

The current study was carried out to isolate and identify Enterococcus species from clinical samples and to analyse the antimicrobial susceptibility pattern of Enterococcus Species. All clinical samples which were received in Microbiology laboratory were included in the study. A total of 2958 samples were received. These 129 Enterococci isolates were obtained over a period of 1 year from various samples namely, urine, blood, pus. Samples were processed for microscopy and culture as per the standard guidelines. all samples were inoculated on MacConkey agar and Blood agar. Identification and antibiotic sensitivity pattern of bacterial isolates were carried out by automated system. i.e. VITEK 2 Compact. Out of 2958 samples, Total 129 samples showed growth of enterococci. Out of 129 isolates, 84 were Enterococcus spp, 18 were E.faecalis, 16 were E.faceium. Out of total 129 samples, 76 samples were of males and 53 were of females. Most common samples from which enterococci were isolated was urine accounting for 85 followed by Pus accounting for 15. Medicine department showed the highest isolates with 88. Out of 129 Enterococci 64 showed resistance to primary line of drug like Benzyl penicillin, 79 Enterococci showed resistance to Ampicillin. Out of 129 enterococci 70 showed resistance to secondary line of drug like tetracycline,59 isolates showed resistance to High level Gentamycin, 41 isolates showed resistance to Vancomycin,23 isolates showed resistance to Linezolid. The strains of Enterococci were multidrug resistant. Anitibiotic selection should be done judiciously based on the antibiotic sensitivity pattern of the organism.