Abstract
The purpose of the study is to examine the antimicrobial efficacy of root extracts of the folklore medicinal plant species, Acalypha fruticosa Forssk by using three alcoholic solvents viz; petroleum ether, ethyl acetate and methanol were tested against ten human pathogenic bacteria viz., Pseudomonas aeruginosa, P. stutzeri, Escherichia coli, Micrococcus sp., Lactobacillus sp., Servatia sp., Moraxetta sp., Bacillus subtilis, B. thuriengensis, and Klebsiella pneumoniae and ten human pathogenic fungi viz., Aspergillus niger, A. flavus, A.baumannii, Fusarium oxysporum, F. solani, Mucor rouxii, Alternaria alternata, Candida albicans, Cladosporium sp. and Rhizopus sp. for assessing the antimicrobial properties by adapting disc diffusion method. The results of the study revealed that all extracts showed varied degree of antimicrobial activity against the tested pathogens. However, the methanol extracts exhibited higher inhibition zone (21.83 mm) against the bacterium, Bacillus subtilis and ethyl acetate extracts showed higher inhibiotion zone (24.83 mm) against the fungus, Rhizopus sp. Results concluded that this spices contain high amount of secondary metabolites due to these metabolites they have high antimicrobial activity and it can be used as good bio- preservater and it can also use for medicinal purpose.
Highlights
Plants have been a valuable source of natural products for a long period of time to maintain human health, especially with more intensive studies in the last decade for natural therapies (Gislene et al, 2000)
The purpose of the study is to examine the antimicrobial efficacy of root extracts of the folklore medicinal plant species, Acalypha fruticosa Forssk by using three alcoholic solvents viz; petroleum ether, ethyl acetate and methanol were tested against ten human pathogenic bacteria viz., Pseudomonas aeruginosa, P. stutzeri, Escherichia coli, Micrococcus sp., Lactobacillus sp., Servatia sp., Moraxetta sp., Bacillus subtilis, B. thuriengensis, and Klebsiella pneumoniae and ten human pathogenic fungi viz., Aspergillus niger, A. flavus, A.baumannii, Fusarium oxysporum, F. solani, Mucor rouxii, Alternaria alternata, Candida albicans, Cladosporium sp. and Rhizopus sp. for assessing the antimicrobial properties by adapting disc diffusion method
This study plant species, Acalypha fruticosa belongs to the family, Euphorbiaceae is one such folklore plant used in traditional system of medicine in Coimbatore district of Tamil Nadu, India
Summary
Plants have been a valuable source of natural products for a long period of time to maintain human health, especially with more intensive studies in the last decade for natural therapies (Gislene et al, 2000). A lot of plants with medicinal value used in the Indian traditional medicine have not yet been characterized for their active principles. One such plant of great medicinal importance is Acalypha fruticosa which are found to have diverse photochemical compounds of medicinal properties. This study plant species, Acalypha fruticosa belongs to the family, Euphorbiaceae is one such folklore plant used in traditional system of medicine in Coimbatore district of Tamil Nadu, India. In Western districts of Tamil Nadu, the plant is administered to treat the diseases like jaundice, fever, and even as an antidote. A root decoction is drunken to treat convulsions, fever, colds and swellings of the scrotum and to treat whooping cough. In the present study, an attempt has been made to focus the plant in this angle and to assess its therapeutic potency
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