Abstract

Medicines on the basis of herbs are increasingly used for treating of many diseases and provide the following actions laxative, hepatoprotective, membrane stabilizing and antimicrobial. The plant Prunus domestica L., family Rosaceae is widely cultivated worldwide. The recent studies have shown that fruits have antioxidant, anticancer, antihyperglycemic, anti-hyperlipidemic, antihypertensive, antiosteoporosis, laxative and hepatoprotective activities. As raw material plum of Ukrainian variety ‘vengerka’ was taken for the research and pectin complex from plum fruits was obtained. The yield of the pectin from the fresh plum fruits was 8,6% of a dry weight. The analysis of plum pectin was performed by HPLC and spectrophotometry methods. 16 amino acids were identified and their contents were determined. It was found that plum pectin contained essential amino acids such as threonine, valine, isoleucine, leucine, phenylalanine, and histidine. The total amount of free and bound amino acids was 33.70 μg/mg, while free amino acids – 1.18 μg/mg. The amount of bound amino acids was 32,52 μg/mg. The content of free amino acids was only 3.50% of the amount of all amino acids found in the pectin complex. L-Aspartic and L-Proline predominated among free amino acids. Among the bound amino acids, L-Aspartic and L-Glutamic acids dominated. The content of the total amount of phenolic compounds calculated with reference to gallic acid in the pectin complex was 0.43%, and the content of hydroxycinnamic acids calculated with reference to chlorogenic acid in this substance was 0.09%.

Highlights

  • Plums are widely cultivated in many countries of the world

  • TThe pectin substance obtained from the plum fruit is a powder of a dark reddish brown color, with a sweet and sour taste, readily soluble in water, insoluble in ethyl and methyl alcohol, chloroform, ether

  • The content of the total amount of phenolic compounds calculated with reference to gallic acid in the pectin complex was 0.43%

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Summary

Introduction

Plums are widely cultivated in many countries of the world. The leaders in the production of plums are China and the USA. Plums are used for food in fresh and dried form, as well as for the preparation of juices, jams and compotes. Consumption of plums may help to control obesity, diabetes, and related cardiovascular diseases [1]. At the Ukrainian pharmaceutical market, there is a complex laxative preparation ‘Regulax’, which includes Senna leaves and fruits, as well as fig and plum fruits. Several substances from plum fruits and leaves, were obtained and their chemical composition and pharmacological activity were studied at the National

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