Abstract
Objective To explore the level of 25-OH vitamin D3 in patients with lupus nephritis(LN) and its association with the activity of disease. Method Clinical data of 154 patients with lupus nephritis in our hospital from January 2008 to May 2015 were collected. Another 63 healthy adults were recruited as normal controls. Results The level of 25-OH vitamin D3 in patients with LN was significantly lower than that in normal controls(P<0.01). The concentration of serum 25-OH vitamin D3 was negatively correlated with 24 h urinary protein(r=-0.18,P=0.02), antinuclear antibody(r=-0.20,P=0.01), SLEDAI scores(r=-0.20,P < 0.01), while positively correlated with serum complement C3(r=0.32,P < 0.01). The 'full-housed' patients with all 5 antibodies positive in renal biopsy had lower level of 25-OH vitamin D(P <0.05). Conclusion The level of 25-OH vitamin D3 in patients with LN is inversely correlated with the disease activity. Key words: Lupus erythematosus, Systemic; Calcifediol; Lupus nephritis
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
