Study into the mechanisms of damage of human placental syncytiotrophoblast. II. Histologic comparison of plasma-induced damage and specific enzymes-induced damage.

Abstract

The microscopic characteristics of in vitro maternal plasma-induced syncytical trophoblast damage were studied. They were compared to structural alterations and/or damage produced by trypsin, pronase, vibrio cholera neuraminidase and deoxyribonuclease. It was found that the plasma-induced syncytiolysis had a distinctive pattern which was different from damage produced by the specific enzymes investigated.