Abstract
Peptidoglycan (PG) sacculus has an important role in determining the shape of many bacterial cells. It is composed of glycan strands cross-linked by peptides into a net enclosing the cell and acting as a mechanical shield which protects the cell from bursting due to high internal (turgor) pressure. Importantly, how peptidoglycan is organized in the sacculus is the key controlling the cell shape. Many cells lose their rod shape and become spherical as perturbation of certain proteins such as MreB is introduced - a process believed to change the PG remodeling.
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