Abstract
An intramolecular ureidoaldehyde condensation, β-keto ester (16) + 1-carbamoylpyrrolidine ((R)-14) → Pyrrolo[1,2-c]pyrimidine derivative (19), is the key step in a seven-step preparation of the enantiopure spiro[pyrano-2:3-pyrrolo[1,2-c]pyrimidine] derivative (23), a potential intermediate for the enantioselective total synthesis of ptilomycin A
Published Version
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